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Hexacoordinated phosphates: how to teach old chiral anions new asymmetric tricks
Author(s) -
Lacour Jerome,
Linder David
Publication year - 2007
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.20124
Subject(s) - enantiopure drug , chemistry , cationic polymerization , reagent , combinatorial chemistry , stereoselectivity , ion , phosphate , pairing , enantioselective synthesis , stereochemistry , organic chemistry , computational chemistry , catalysis , physics , superconductivity , quantum mechanics
Chemical reactions and processes often involve chiral, yet racemic, cationic reagents, intermediates, or products. To afford instead nonracemic or enantiopure compounds, an asymmetric ion pairing of the cations with enantiopure anions can be considered—the counter ions behaving as asymmetric auxiliaries, ligands, or reagents. Detailed herein is a short review of our approach toward gaining reliable and predictable control over stereoselective ion pairing phenomena through the synthesis and use of novel configurationally stable hexacoordinated phosphate anions. © 2007 The Japan Chemical Journal Forum and Wiley Periodicals, Inc. Chem Rec 7: 275–285; 2007: Published online in Wiley InterScience ( www.interscience.wiley.com ) DOI 10.1002/tcr.20124