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Reflections on the discovery of nature’s pathways to vitamin B 12
Author(s) -
Scott A. Ian
Publication year - 2001
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.1009
Subject(s) - corrin , vitamin b12 , perspective (graphical) , biology , chemistry , biochemistry , computer science , artificial intelligence
The chronology of the discoveries along the pathway of vitamin B 12 biosynthesis is reviewed from a personal perspective, including discussion of the most recent finding that two pathways to B 12 exist—one aerobic and one anaerobic—which differ mainly in the ring contraction mechanisms which convert porphyrin to corrin. © 2001 John Wiley & Sons, Inc. and The Japan Chemical Journal Forum Chem Rec 1:212–227, 2001
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