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Increased postsynaptic Ca 2+ reduces mini frequency at the Drosophila larval NMJ
Author(s) -
Powers Andrew S.,
Grizzaffi Jeffrey,
Lnenicka Gregory A.
Publication year - 2017
Publication title -
synapse
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.809
H-Index - 106
eISSN - 1098-2396
pISSN - 0887-4476
DOI - 10.1002/syn.21971
Subject(s) - postsynaptic potential , excitatory postsynaptic potential , post tetanic potentiation , neuromuscular junction , drosophila (subgenus) , postsynaptic current , inhibitory postsynaptic potential , postsynaptic density , stimulation , neuroscience , biology , microbiology and biotechnology , chemistry , receptor , biochemistry , gene
Repetitive stimulation of the Drosophila larval NMJ can produce a reduction in the frequency of miniature excitatory postsynaptic currents. By buffering postsynaptic Ca 2+ , it was shown that the decrease in “mini” frequency was due to an increase in postsynaptic Ca 2+ .