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Low startle magnitude may be a behavioral marker of vulnerability to cocaine addiction
Author(s) -
Wheeler Marina G.,
Duncan Erica,
Davis Michael
Publication year - 2017
Publication title -
synapse
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.809
H-Index - 106
eISSN - 1098-2396
pISSN - 0887-4476
DOI - 10.1002/syn.21943
Subject(s) - vulnerability (computing) , abstinence , addiction , psychology , neuroscience , psychiatry , computer security , computer science
Cocaine addicted men have low startle magnitude persisting during prolonged abstinence. Low startle rats show greater cocaine self‐administration than high startle rats. Low startle may be a marker of a vulnerability to heightened cocaine‐related behaviors in rats and similarly may be a marker of vulnerability to cocaine addiction in humans.