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The selective dopamine D 3 receptor antagonist SB‐277011A significantly accelerates extinction to environmental cues associated with cocaine‐induced place preference in male sprague‐dawley rats
Author(s) -
Ashby Charles R.,
Rice Onarae V.,
Heidbreder Christian A.,
Gardner Eliot L.
Publication year - 2015
Publication title -
synapse
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.809
H-Index - 106
eISSN - 1098-2396
pISSN - 0887-4476
DOI - 10.1002/syn.21839
Subject(s) - conditioned place preference , extinction (optical mineralogy) , dopamine , antagonist , pharmacology , addiction , conditioning , psychology , self administration , classical conditioning , unconditioned stimulus , neuroscience , chemistry , receptor , medicine , mineralogy , statistics , mathematics
The authors show that the dopamine D3 antagonist SB‐277011‐A significantly accelerated the extinction of a conditioned place preference to cocaine in a dose‐dependent manner.