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Preparation and Characterization of a Hard Capsule Based on Oxidized Rice Starch and Cellulose Nanocrystals
Author(s) -
Chen QiJie,
Zhao YaLan,
Zong ZhangYang,
You Na,
Zhang Peng
Publication year - 2021
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.202100085
Subject(s) - materials science , fourier transform infrared spectroscopy , plasticizer , starch , cellulose , ultimate tensile strength , scanning electron microscope , glycerol , compatibility (geochemistry) , chemical engineering , composite number , capsule , composite material , polymer chemistry , chemistry , organic chemistry , botany , engineering , biology
A hard capsule based on oxidized rice starch (ORS) and cellulose nanocrystals (CNC) is prepared by a dipping method and the glycerol and carrageenan are used as a plasticizer and gelling agent in the ORS/CNC gel solution, respectively. The viscosity of gel solution that is suitable for film‐forming/capsule‐forming is analyzed. When the content of CNC is 8.0%, the tensile strength of the ORS/CNC composite film is 10.09 MPa and increased by 196.0%. The loss on drying and the disintegration time of the ORS/CNC capsules are also investigated. The ORS/CNC capsules are analyzed by Fourier Transform Infrared spectroscopy (FTIR), X‐Ray Diffraction (XRD), and Scanning Electron Microscopy (SEM). The results show that the ORS and CNC have good compatibility and good film‐forming ability and can be used as excipients to prepare the hard capsules.