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Films Fabricated with Native and Ball‐Milled Modified Glutinous Rice Starch: Physicochemical and Mucoadhesive Properties
Author(s) -
Soe May Thu,
Pongjanyakul Thaned,
Limpongsa Ekapol,
Jaipakdee Napaphak
Publication year - 2021
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.202000012
Subject(s) - plasticizer , materials science , glycerol , starch , ultimate tensile strength , fourier transform infrared spectroscopy , chemical engineering , swelling , polymer , modified starch , polymer chemistry , composite material , nuclear chemistry , chemistry , food science , organic chemistry , engineering
This study aims to investigate the physicochemical and mucoadhesive properties of films made of glutinous rice starch (GRS), native (NGRS), and ball‐milled modified GRS (MGRS), in comparison with the reference mucoadhesive polymers. By using the solvent casting technique with glycerol (30% w/w of starch mass) as a plasticizer, all GRS films exhibit satisfactory and comparable thickness and weight uniformity, surface pH, and moisture content. ATR‐FTIR indicates that the hydrogen bonds are formed between GRS and glycerol. The absence of crystalline structure of GRS in glycerol plasticized films is confirmed using ATR‐FTIR and XRD. The films made of NGRS and MGRS have similar swelling behavior (751 ± 75 to 1002 ± 104%), whereas those made of longer milling time MGRS demonstrate higher erosion (27.1 ± 4.2%) ( p < 0.05). MGRS films exhibit greater flexibility with lower tensile strength (9.6 ± 1.7 to 9.8 ± 1.0 MPa) but higher elongation (162.5 ± 6.5 to 165.7 ± 2.5%) compared to native systems (13.7 ± 0.5 MPa and 128.1 ± 5.0%, respectively) ( p < 0.05). The MGRS films show comparable mucoadhesiveness expressed as detachment force and work of adhesion to those of sodium carboxymethylcellulose, but higher than those of NGRS, hydroxypropyl methylcellulose, and chitosan ( p < 0.05). This study reveals the potential exploitation of GRS as a mucoadhesive film former for pharmaceutical application.