Premium
Synthesis of aminopyridinium‐grafted starch derivatives and evaluation of their antioxidant property
Author(s) -
Tan Wenqiang,
Guo Zhanyong,
Chen Qiuhong,
Dong Fang,
Li Qing
Publication year - 2017
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.201600259
Subject(s) - starch , antioxidant , dpph , chemistry , radical , modified starch , hydroxyl radical , pyridinium , organic chemistry
In order to improve the bioactivity of starch, novel starch derivatives were developed including 2‐(2‐aminopyridinium)acetyl starch (2APASC), 2‐(3‐aminopyridinium)acetyl starch (3APASC), 2‐(4‐aminopyridinium)acetyl starch (4APASC), 2‐(2,3‐diaminopyridinium)acetyl starch (2,3DAPASC), 2‐(2,6‐diaminopyridinium)acetyl starch (2,6DAPASC), and 2‐(3,4‐diaminopyridinium)acetyl starch (3,4DAPASC). The in vitro antioxidant capacities against hydroxyl‐radical, DPPH‐radical, and superoxide‐radical for all synthesized starch derivatives were evaluated using free radicals scavenging assays. The results showed that the scavenging effect of starch derivatives bearing aminopyridinium groups was better than starch. Especially, 2,3DAPASC and 2,6DAPASC could scavenge hydroxyl‐radicals completely at 0.4 mg/mL. Moreover, the antioxidant property of synthesized starch derivatives was affected by the different positions and the number of amino groups on pyridinium rings. Because the aminopyridinium acetyl starch derivatives could be synthesized conveniently and also possessed significantly strong antioxidant activity, this synthetic strategy might provide an effective tool to broaden further utilization of starch.