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Seaweed polysaccharides and their potential biomedical applications
Author(s) -
Venkatesan Jayachandran,
Lowe Baboucarr,
Anil Sukumaran,
Manivasagan Panchanathan,
Kheraif Abdulaziz A Al,
Kang KyongHwa,
Kim SeKwon
Publication year - 2015
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.201400127
Subject(s) - fucoidan , polysaccharide , tissue engineering , drug delivery , carrageenan , biocompatibility , self healing hydrogels , extracellular matrix , chemistry , microbiology and biotechnology , nanotechnology , biomedical engineering , materials science , biochemistry , biology , medicine , organic chemistry
Over the past two decades numerous studies have been reported on seaweeds‐derived polysaccharides for biomedical and biological applications (tissue engineering, drug delivery, wound healing, and biosensor). Alginate, carrageenan, fucoidan, and ulvan are widely used marine derived polysaccharides for biological and biomedical applications due to their biocompatibility and availability. The gel forming property of alginate has increased its applications in tissue engineering and drug delivery as an extracellular matrix and delivery vehicle, respectively. Other sulfated polysaccharides such as carrageenan and fucoidan show promising application in tissue engineering due to their capacity of inducing important osteogenic, adipogenic, and chondrogenic differentiation in stem cells. In this review, we explained the extraction/isolation methods and applications of these seaweed derived polysaccharides as well as their roles in therapeutics, drug delivery, and tissue engineering.