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Application of Cyclodextrins in the Chromatography
Author(s) -
Szejtli J.
Publication year - 1987
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.19870391006
Subject(s) - cyclodextrin , chromatography , chemistry , polarity (international relations) , molecule , gas chromatography , organic chemistry , biochemistry , cell
The central cavity of the cylinder‐shaped cyclodextrin molecules behaves as an empty molecular capsule: it can accomodate so called ‘guest molecules’ of appropriate size, shape and polarity. The stability of the formed inclusion complexes is however very different. This is the basis of the separation of various substances by cyclodextrins. The separation can be realized by non‐chromatographic methods or by chromatographic methods. The present review summarizes the utilization of cyclodextrins and their derivatives in gas‐liquid and gas‐solid‐, gel‐, inclusion‐, thin‐layer‐, affinity‐, and high performance liquid chromatography.