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Synthesis and 13 C‐NMR Spectroscopy of Methylated beta‐Cyclodextrins
Author(s) -
Szejtli J.,
Lipták A.,
Jodál I.,
Fügedi P.,
Nánási P.,
Neszmélyi A.
Publication year - 1980
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.19800320506
Subject(s) - nuclear magnetic resonance spectroscopy , chemistry , cyclodextrin , spectroscopy , carbon 13 nmr , crystallography , stereochemistry , organic chemistry , physics , quantum mechanics
The methylated analogues of ß‐cyclodextrin dissolve in cold water 10 – 20 times better than ß‐cyclodextrin itself, however, quite unusually on heating they crystallize from the solution. The structure of heptakis‐(2,6‐di‐O‐methyl)‐ and heptakis‐(2,3,6‐tri‐O‐methyl)‐ß‐cyclodextrin was proved by gas‐liquid chromatographic and 1 H‐NMR and 13 C‐NMR spectroscopic investigations. The corresponding model compounds were synthetized and, according to 13 C‐NMR spectroscopic investigations, a part of the so far published NMR assignations have to be corrected.