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Hydroxyethyl Starch as a Cryoprotective Agent for Human Red Blood Cells The Relation Between the Molecular Properties and the Cryoprotective Effect
Author(s) -
Greenwood C. T.,
Muir D. D.,
Whitcher H. W.
Publication year - 1977
Publication title -
starch ‐ stärke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 82
eISSN - 1521-379X
pISSN - 0038-9056
DOI - 10.1002/star.19770291005
Subject(s) - hydroxyethyl starch , starch , human blood , chemistry , blood preservation , biochemistry , biology , physiology
The use of hydroxyethyl starch (HES) as a cryoprotective agent for human erythrocytes is examined in detail. The molecular properties of the HES pertinent to cryoprotection are described and some conditions for the optimal use of HES in this role are defined. In agreement with the results of other workers, HES is shown to afford a considerable amount of protection to human red blood cells during freezing.