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Back Cover: Development and validation of a quality by design enabled robust LC method for estimation of daptomycin in pharmaceutical dosage form
Author(s) -
Panda Sagar Suman,
Bera Ravi Kumar Venkata Varaha,
Pradhan Swati Swagatika
Publication year - 2019
Publication title -
separation science plus
Language(s) - English
Resource type - Journals
ISSN - 2573-1815
DOI - 10.1002/sscp.201970045
Subject(s) - daptomycin , quality by design , robustness (evolution) , computer science , estimation , cover (algebra) , reliability engineering , biochemical engineering , risk analysis (engineering) , data mining , engineering , chemistry , medicine , operations management , biology , systems engineering , mechanical engineering , vancomycin , bacteria , downstream (manufacturing) , genetics , staphylococcus aureus , biochemistry , gene
DOI: 10.1002/sscp.201900062 The cover picture shows a rapid QbD approach for robust liquid chromatographic estimation of daptomycin in dosage form. This approach defined ATP & CAAs for the method, identified CMVs using risk scores and established control strategy for monitoring method performance. Further, ATP was achieved by integrating YRT approach for assuring method robustness and identifying CMVs to be monitored for continuous improvement of method performance throughout the method lifecycle.