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Inside Front Cover: Analytical lifecycle management approach: Application to development of a reliable LC method for estimation of lacidipine
Author(s) -
Panda Sagar Suman,
Bera Ravi Kumar Venkata Varaha,
Acharjya Sasmita Kumari,
Sahoo Padmalaya,
Beg Sarwar
Publication year - 2019
Publication title -
separation science plus
Language(s) - English
Resource type - Reports
ISSN - 2573-1815
DOI - 10.1002/sscp.201970004
Subject(s) - lacidipine , cover (algebra) , front cover , process development , computer science , domain (mathematical analysis) , chromatography , process engineering , mathematics , chemistry , engineering , mechanical engineering , mathematical analysis , biochemistry , receptor , antagonist
Sep Sci plus 2019;2:18–25. DOI: 10.1002/sscp.201800110 The cover picture shows the holistic ALM approach for developing an efficient liquid chromatographic method for estimating lacidipine present in pharmaceuticals. This approach established ATP & CQAs for the method, identified the CMVs using QRM tools and employed DoE domain for optimizing the chromatographic process. Further, demarcation of control space and subsequent continual monitoring developed a rapid, robust and reliable analytical method for lacidipine with federal flexibilities.