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Single‐Molecule Spatial Arrangement: Strep ‐Tag II and Monovalent Strep ‐Tactin as Novel Handles in Single‐Molecule Cut‐and‐Paste (Small Methods 8/2017)
Author(s) -
Erlich Katherine R.,
Baumann Fabian,
Pippig Diana A.,
Gaub Hermann E.
Publication year - 2017
Publication title -
small methods
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.66
H-Index - 46
ISSN - 2366-9608
DOI - 10.1002/smtd.201770081
Subject(s) - biomolecule , cantilever , cover (algebra) , molecule , nanotechnology , nanoscopic scale , nanometre , materials science , computer science , chemistry , crystallography , engineering , mechanical engineering , organic chemistry , composite material
The cover image is a conceptual representation of the process of “single‐molecule cut‐and‐paste”, a technique that enables directed assembly of nanoscale structures, which is presented by Hermann E. Gaub and co‐workers in article number 1700169 . The storage area “A” of the surface contains several depot areas of biomolecules of interest. These biomolecules (represented by the colored fundamental shapes) are picked up one‐by‐one by the cantilever via a specific handling system (represented here by the hooks and eyelet). The molecules can then be arranged on the target area “B” in any geometry with nanometer‐precision. Cover image by Christoph Hohmann, Nanosystems Initiative Munich (NIM).