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Peptide‐Based Nanocarriers for Cancer Therapy
Author(s) -
Wei Guoqing,
Wang Yi,
Huang Xuehui,
Hou Huabo,
Zhou Shaobing
Publication year - 2018
Publication title -
small methods
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.66
H-Index - 46
ISSN - 2366-9608
DOI - 10.1002/smtd.201700358
Subject(s) - nanocarriers , drug delivery , peptide , biocompatibility , cancer therapy , nanotechnology , targeted drug delivery , nanoparticle , in vivo , drug , bioavailability , materials science , chemistry , pharmacology , cancer , medicine , biochemistry , biology , organic chemistry , microbiology and biotechnology
Peptides, which are made up of amino acids, are an excellent candidate as a composition component of a nanocarrier for drug delivery due to their biocompatibility, bioavailability, and stability in vivo. Here, the progress in peptides as nanocarriers for applications in cancer therapy are summarized, including as a nanocarrier matrix for self‐assembled nanoparticles, as surface modification moieties of nanocarriers for targeting and/or penetrating function, and as enzyme‐responsive linkers of nanoparticles for triggering drug release. Peptide‐based nanocarriers should receive more attention, and they have great potential in biomedical applications.