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Biochips—New Platforms for Cell‐Based Immunological Assays
Author(s) -
Shao Ning,
Qin Lidong
Publication year - 2018
Publication title -
small methods
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.66
H-Index - 46
ISSN - 2366-9608
DOI - 10.1002/smtd.201700254
Subject(s) - biochip , computer science , microscale chemistry , immune system , nanotechnology , data science , medicine , immunology , materials science , mathematics , mathematics education
Abstract Considerable advances have been witnessed in the development of biochips that seek to realize various types of immune cell analysis on microscale platforms and enhance both basic and applied immunological research beyond the capability of conventional methods. Here, state‐of‐the‐art designs and examples for biochip‐based analysis and manipulation of immune cells are reviewed, and the potential of this emerging technology to enhance the understanding of immunology and improve disease diagnosis and treatment is discussed. In particular, some of the recent advances in this field, along with the challenges that must be addressed for these technologies, and their potential in precision medicine are highlighted.