Microfluidics: Stochastic and Age‐Dependent Proteostasis Decline Underlies Heterogeneity in Heat‐Shock Response Dynamics (Small 30/2021) | Zendy

VerttiQuintero Nadia | Zendy; Berger Simon | Zendy; Casadevall i Solvas Xavier | Zendy; Statzer Cyril | Zendy; Annis Jillian | Zendy; Ruppen Peter | Zendy; Stavrakis Stavros | Zendy; Ewald Collin Y. | Zendy; Gunawan Rudiyanto | Zendy; deMello Andrew J. | Zendy

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Microfluidics: Stochastic and Age‐Dependent Proteostasis Decline Underlies Heterogeneity in Heat‐Shock Response Dynamics (Small 30/2021)

Author(s) -

VerttiQuintero Nadia,

Berger Simon,

Casadevall i Solvas Xavier,

Statzer Cyril,

Annis Jillian,

Ruppen Peter,

Stavrakis Stavros,

Ewald Collin Y.,

Gunawan Rudiyanto,

deMello Andrew J.

Publication year - 2021

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.202170157

Subject(s) - proteostasis , shock (circulatory) , microfluidics , biology , heat shock protein , heat shock , dynamics (music) , hsf1 , throughput , sorting , microbiology and biotechnology , nanotechnology , computer science , genetics , materials science , physics , medicine , gene , hsp70 , telecommunications , wireless , programming language , acoustics

In article number 2102145, Collin Y. Ewald, Rudiyanto Gunawan, and co‐workers highlight a microfluidic device used for sorting adult C. elegans populations—in a high‐throughput manner—based on individual GFP expression. The heterogeneous dynamic heat‐shock response, its relation to proteostasis, and how it can predict lifespan are thoroughly studied. Image credit: Mrs. Yujia Ma.

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