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Noncontact Multiphysics Probes: Noncontact Multiphysics Probe for Spatiotemporal Resolved Single‐Cell Manipulation and Analyses (Small 24/2021)
Author(s) -
Brimmo Ayoola T.,
Menachery Anoop,
Sukumar Pavithra,
Qasaimeh Mohammad A.
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202170118
Subject(s) - multiphysics , microfluidics , nanotechnology , materials science , single cell analysis , membrane , biomedical engineering , biophysics , cell , chemistry , finite element method , physics , engineering , biology , biochemistry , thermodynamics
In article number 2100801, Mohammad A. Qasaimeh and co‐workers develop a noncontact multiphysics probe (NMP) for minimally invasive manipulation of single cells within the tissue formation. It works in an open microfluidic setting and simultaneously confines reagents and electric field for macromolecules exchange through the membrane of living single‐cells. These features enable transfection, biopsy and tweezing operations on single‐cells within the tissue formation.