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Advanced Cardiac Models: Considerations for the Bioengineering of Advanced Cardiac In Vitro Models of Myocardial Infarction (Small 15/2021)
Author(s) -
Sharma Poonam,
Wang Xiaowei,
Ming Clara Liu Chung,
Vettori Laura,
Figtree Gemma,
Boyle Andrew,
Gentile Carmine
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202170067
Subject(s) - myocardial infarction , ex vivo , in vivo , medicine , computer science , cardiology , biology , microbiology and biotechnology
In article number 2003765, Carmine Gentile and co‐workers describe the major pathophysiological features required for the bioengineering of a heart attack in a Petri dish. The article presents a thorough comparison of current in vitro, ex vivo, and in vivo models. It also explores the potential use of latest technologies for advanced cardiac models, such as 3D bioprinting, microfluidic devices and patient‐derived stem cell, with the potential to develop personalized novel therapies for heart attack patients.