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Bone Formation: Rolled‐Up Metal Oxide Microscaffolds to Study Early Bone Formation at Single Cell Resolution (Small 12/2021)
Author(s) -
Herzer Raffael,
Gebert Annett,
Hempel Ute,
Hebenstreit Franziska,
Oswald Steffen,
Damm Christine,
Schmidt Oliver G.,
MedinaSánchez Mariana
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202170053
Subject(s) - materials science , microstructure , nanotechnology , cell adhesion , metal , adhesion , bone formation , mineralization (soil science) , bone tissue , biomedical engineering , metallurgy , composite material , chemistry , biology , medicine , organic chemistry , nitrogen , endocrinology
Transparent Ti‐45Nb 3D microstructures offer an elegant way to study single bone cell‐implant material interactions and pore size effects in vitro. In article number 2005527, Mariana Medina‐Sánchez and co‐workers present this technology as an excellent tool to live monitor cell migration and adhesion behavior changes deriving from highly constricted microenvironments, while also providing deeper insights on cell death related bone mineralization processes in low nutrition conditions.