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Antimicrobial Peptides: Cross‐Strand Interaction, Central Bending, and Sequence Pattern Act as Biomodulators of Simplified β‐Hairpin Antimicrobial Amphiphiles (Small 7/2021)
Author(s) -
Shao Changxuan,
Zhu Yongjie,
Jian Qiao,
Lai Zhenheng,
Tan Peng,
Li Guoyu,
Shan Anshan
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202170029
Subject(s) - amphiphile , antimicrobial , peptide , combinatorial chemistry , sequence (biology) , antimicrobial peptides , chemistry , nanotechnology , materials science , computational biology , biochemistry , biology , organic chemistry , polymer , copolymer
In article number 2003899, Anshan Shan and co‐workers establish a progressive screening system to obtain simplified, potent and nontoxic β‐hairpin amphipathic prototypes against bacterial infections. Functional optimization triggered by the delicate balance of biomodulators could facilitate the advancement of peptide‐based antimicrobial biomaterials.