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Droplet Microfluidics: High‐Throughput Optimization of Recombinant Protein Production in Microfluidic Gel Beads (Small 2/2021)
Author(s) -
Napiorkowska Marta,
Pestalozzi Luzius,
Panke Sven,
Held Martin,
Schmitt Steven
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202170004
Subject(s) - microfluidics , recombinant dna , nanotechnology , throughput , materials science , bead , chemistry , biochemistry , computer science , telecommunications , wireless , gene , composite material
In article number 2005523, Steven Schmitt and co‐workers present microfluidic optimization of biotechnological protein production. The artwork displays a series of gel beads, each containing a colony of Komagataella phaffii secreting a protein that is captured and fluorescently labeled within the beads. Laser‐based analysis identifies high‐producing clones.