Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020) | Zendy

Huang Rongtao | Zendy; Ding Zhaoyang | Zendy; Jiang BangPing | Zendy; Luo Zilan | Zendy; Chen Ting | Zendy; Guo Zhengxi | Zendy; Ji ShiChen | Zendy; Liang Hong | Zendy; Shen XingCan | Zendy

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Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020)

Author(s) -

Huang Rongtao,

Ding Zhaoyang,

Jiang BangPing,

Luo Zilan,

Chen Ting,

Guo Zhengxi,

Ji ShiChen,

Liang Hong,

Shen XingCan

Publication year - 2020

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.202070254

Subject(s) - ovalbumin , metalloprotein , in situ , cancer research , tumor microenvironment , photodynamic therapy , reactive oxygen species , catalysis , chemistry , antigen , enzyme , medicine , tumor cells , biochemistry , immunology , organic chemistry

In article number 2004345, Bang‐Ping Jiang, Xing‐Can Shen, and co‐workers develop one type of brand‐new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating “phototherapy‐enzymatic” RuO 2 and model antigen ovalbumin. This ushers a prospect of concurrently enhancing photodynamic therapy and reversing the immunosuppressive tumor microenvironment by in situ catalyzing overexpressed H 2 O 2 to produce O 2 .

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