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DNA Tandem Repeats: A Simple Blocking PCR‐Based Method for the Synthesis of High‐Copy dsDNA Tandem Repeats (Small 43/2020)
Author(s) -
Wang Xin,
Yang Xuerui
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070234
Subject(s) - tandem repeat , dna , direct repeat , microsatellite , tandem , sequence (biology) , biology , microbiology and biotechnology , genetics , genome , base sequence , gene , materials science , allele , composite material
High‐copy DNA repeats are building blocks of complex DNA superstructures. It has not been a trivial task to make a short DNA sequence elongated by simply repeating itself. In article number 2003671, Xin Wang and Xuerui Yang present a simple method named BPRE, which now makes mass production of the high‐copy DNA repeats fast, cheap, and clean. As a typical application, reannealing of the DNA repeats generates elastic hydrogels with high capacity of drug absorption and prolonged release.