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Cancer Therapy: Transformable Dual‐Inhibition System Effectively Suppresses Renal Cancer Metastasis through Blocking Endothelial Cells and Cancer Stem Cells (Small 40/2020)
Author(s) -
Wang Lu,
Lv Yulin,
Li Cong,
Yang Guang,
Fu Bo,
Peng Qiang,
Jian Lingrui,
Hou Dayong,
Wang Jiaqi,
Zhao Changhao,
Yang Peipei,
Zhang Kuo,
Wang Lei,
Wang Ziqi,
Wang Hao,
Xu Wanhai
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070222
Subject(s) - cancer , metastasis , cancer metastasis , cancer cell , cancer research , modular design , cancer stem cell , blocking (statistics) , cancer therapy , medicine , computer science , computer network , operating system
In article number 2004548, Lei Wang, Ziqi Wang, Hao Wang, Wanhai Xu, and co‐workers propose a transformable dual‐inhibition system (TDS) based on a self‐assembly peptide to reduce metastasis of renal cancer via the inhibition of neovascular endothelial cells and cancer stem cells simultaneously. The TDS has great value in suppressing renal cancer metastasis. Additionally, this newly developed TDS also gives new ideas for in situ constructed modular functional materials and diverse bio‐applications.