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Small Extracellular Vesicles: High‐Fidelity Determination and Tracing of Small Extracellular Vesicle Cargoes (Small 40/2020)
Author(s) -
Chen Xiaohui,
Jia Mei,
Liu Lianhua,
Qiu Xiaopei,
Zhang Hong,
Yu Xingle,
Gu Wei,
Qing Guangchao,
Li Qingmei,
Hu Xiaolin,
Wang Ruixuan,
Zhao Xianxian,
Zhang Liangliang,
Wang Xianfeng,
Durkan Colm,
Wang Nan,
Wang Guixue,
Luo Yang
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070218
Subject(s) - extracellular vesicle , extracellular vesicles , vesicle , extracellular , tracing , microvesicles , microbiology and biotechnology , nanoprobe , nanotechnology , chemistry , rna , biophysics , microrna , biology , materials science , biochemistry , computer science , gene , membrane , nanoparticle , operating system
In article number 2002800, Guixue Wang, Yang Luo, and co‐workers introduce a DNA origami nanoprobe “fLIGHT” for high‐fidelity visualization of small extracellular vesicle microRNAs without RNA extraction. This innovative platform can aid in easy development of a universal molecular detection strategy that could facilitate extracellular vesicle‐derived fundamental biological studies.