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Food Additives: Foodborne Titanium Dioxide Nanoparticles Induce Stronger Adverse Effects in Obese Mice than Non‐Obese Mice: Gut Microbiota Dysbiosis, Colonic Inflammation, and Proteome Alterations (Small 36/2020)
Author(s) -
Cao Xiaoqiong,
Han Yanhui,
Gu Min,
Du Hengjun,
Song Mingyue,
Zhu Xiaoai,
Ma Gaoxing,
Pan Che,
Wang Weicang,
Zhao Ermin,
Goulette Timothy,
Yuan Biao,
Zhang Guodong,
Xiao Hang
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070199
Subject(s) - dysbiosis , gut flora , adverse effect , inflammation , medicine , obesity , mucosal inflammation , proteome , immunology , chemistry , food science , pharmacology , biochemistry
In article number 2001858, Hang Xiao and co‐workers study how oral consumption of food additive TiO 2 (E171, 112 nm) or TiO 2 nanoparticles (NPs) (33 nm) leads to a series of adverse effects in mice, such as gut microbiota dysbiosis, colonic inflammation, and altered hepatic and colonic proteome. Importantly, TiO 2 NPs produce stronger adverse effects than TiO 2 (E171), and obese mice are more susceptible to these effects.