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Cancer Therapy: A Glucose/Oxygen‐Exhausting Nanoreactor for Starvation‐ and Hypoxia‐Activated Sustainable and Cascade Chemo‐Chemodynamic Therapy (Small 31/2020)
Author(s) -
Guo Yuxin,
Jia HaoRan,
Zhang Xiaodong,
Zhang Xinping,
Sun Qing,
Wang ShaoZhe,
Zhao Jing,
Wu FuGen
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070174
Subject(s) - nanoreactor , hypoxia (environmental) , cancer therapy , oxygen , chemistry , cancer , cancer research , medicine , biochemistry , catalysis , organic chemistry
Sustainable and cascade anticancer strategies have attracted great attention due to their excellent therapeutic performance. In article number 2000897, Fu‐Gen Wu and co‐workers present a self‐amplified nanoreactor for cancer treatment. The nanoreactor can convert oxygen into HO• for chemodynamic therapy, consume glucose for starvation therapy, and provide a hypoxic environment for hypoxia‐activated chemotherapy.