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Cerium Oxide Nanoparticles: Cerium Oxide Nanoparticles: Advances in Biodistribution, Toxicity, and Preclinical Exploration (Small 20/2020)
Author(s) -
Casals Eudald,
Zeng Muling,
ParraRobert Marina,
FernándezVaro Guillermo,
MoralesRuiz Manuel,
Jiménez Wladimiro,
Puntes Víctor,
Casals Gregori
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070111
Subject(s) - cerium oxide , biodistribution , nanoparticle , cerium , toxicity , nanotechnology , materials science , oxide , chemistry , pharmacology , medicine , inorganic chemistry , organic chemistry , biochemistry , in vitro
The benefits of classic antioxidants can be translated to clinical therapies owing to the superior activity of CeO 2 nanoparticles as redox buffers. In article number 1907322, Wladimiro Jiménez, Víctor Puntes, Gregori Casals, and co‐workers present a historical background of their development for medicine, and analyze their pharmacokinetics, toxicity, and therapeutic value, focusing on the liver where they accumulate. Finally, considerations for medical nanoparticles to reach the clinic are discussed in detail.