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Nuclear Mechanics: Nuclear Mechanics within Intact Cells Is Regulated by Cytoskeletal Network and Internal Nanostructures (Small 18/2020)
Author(s) -
Zhang Jitao,
Alisafaei Farid,
Nikolić Miloš,
Nou Xuefei A.,
Kim Hanyoup,
Shenoy Vivek B.,
Scarcelli Giuliano
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070098
Subject(s) - cytoskeleton , nanostructure , biophysics , brillouin zone , mechanics , physics , materials science , nanotechnology , chemistry , biology , optics , cell , biochemistry
In article number 1907688, Vivek B. Shenoy, Giuliano Scarcelli, and co‐workers use all‐optical Brillouin microscopy and 3D chemomechanical modeling to investigate the regulation of nuclear mechanics. It is observed that the nuclear modulus can be modulated by both epigenetic regulation targeting internal nanostructures and cytoskeletal behavior through a robust mechanism conserved in different culturing conditions.