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Cancer Spheroids: Super‐Resolution Mapping of Single Nanoparticles inside Tumor Spheroids (Small 6/2020)
Author(s) -
Liu Yongtao,
Wang Fan,
Lu Hongxu,
Fang Guocheng,
Wen Shihui,
Chen Chaohao,
Shan Xuchen,
Xu Xiaoxue,
Zhang Lin,
Stenzel Martina,
Jin Dayong
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070030
Subject(s) - spheroid , materials science , nanoparticle , optics , scattering , absorption (acoustics) , bessel beam , resolution (logic) , saturation (graph theory) , nanotechnology , beam (structure) , chemistry , physics , computer science , mathematics , combinatorics , biochemistry , artificial intelligence , in vitro
In article number 1905572, Fan Wang and co‐workers develop near‐infrared Bessel‐beam emission saturation nanoscopy to simultaneously tackle the problems in light absorption and scattering for biological tissues, enabling the tracking of single nanoparticles inside a multicellular tumor spheroid in the depth over 55 µm with an imaging resolution of sub‐98 nm.