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Endovascular Embolization: Injectable and Radiopaque Liquid Metal/Calcium Alginate Hydrogels for Endovascular Embolization and Tumor Embolotherapy (Small 2/2020)
Author(s) -
Fan Linlin,
Duan Minghui,
Xie Zhongchen,
Pan Keqin,
Wang Xuelin,
Sun Xuyang,
Wang Qian,
Rao Wei,
Liu Jing
Publication year - 2020
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202070011
Subject(s) - biocompatibility , embolization , radiodensity , self healing hydrogels , materials science , biomedical engineering , in vivo , radiology , medicine , polymer chemistry , radiography , metallurgy , microbiology and biotechnology , biology
A new conceptual injectable and radiopaque liquid metal/calcium alginate (LM/CA) hydrogel is proposed and demonstrated in article number 1903421 by Jing Liu and co‐workers for endovascular embolization and tumor embolotherapy. It is shown that such a hydrogel displays high flexibility and radiopacity due to the introduction of LM droplets. It also owns excellent biocompatibility and hemocompatibility to facilitate future clinical applications regarding endovascular embolization. A series of in vivo animal experiments on the LM/CA hydrogel for innovative tumor embolotherapy achieve rather promising therapeutic effects.