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Structure Engineering of Yolk–Shell Magnetic Mesoporous Silica Microspheres with Broccoli‐Like Morphology for Efficient Catalysis and Enhanced Cellular Uptake
Author(s) -
Pan Panpan,
Yue Qin,
Yang Xuanyu,
Ren Yuan,
Alharthi Fahad A.,
Alghamdi Abdulaziz,
Su Jiacan,
Deng Yonghui
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202006925
Subject(s) - materials science , mesoporous material , nanotechnology , mesoporous silica , chemical engineering , superparamagnetism , nanomaterial based catalyst , microsphere , biocompatibility , drug delivery , nanoparticle , nanorod , catalysis , chemistry , organic chemistry , magnetization , magnetic field , physics , quantum mechanics , engineering , metallurgy
Abstract Yolk–shell magnetic mesoporous microspheres exhibit potential applications in biomedicine, bioseparation, and catalysis. Most previous reports focus on establishing various interface assembly strategies to construct yolk–shell mesoporous structures, while little work has been done to control their surface topology and study their relevant applications. Herein, a unique kind of broccoli‐like yolk–shell magnetic mesoporous silica (YS‐BMM) microsphere is fabricated through a surfactant‐free kinetic controlled interface assembly strategy. The obtained YS‐BMM microspheres possess a well‐defined structure consisting of a magnetic core, middle void, mesoporous silica shell with tunable surface roughness, large superparamagnetism (36.4 emu g −1 ), high specific surface area (174 m 2 g −1 ), and large mesopores of 10.9 nm. Thanks to these merits and properties, the YS‐BMM microspheres are demonstrated to be an ideal support for immobilization of ultrafine Pt nanoparticles (≈3.7 nm) and serve as superior nanocatalysts for hydrogenation of 4‐nitrophenol with yield of over 90% and good magnetic recyclability. Furthermore, YS‐BMM microspheres show excellent biocompatibility and can be easily phagocytosed by osteoclasts, revealing a potential candidate in sustained drug release in orthopedic disease therapy.