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Requirements for Animal Experiments: Problems and Challenges
Author(s) -
Fontana Flavia,
Figueiredo Patrícia,
Martins João P.,
Santos Hélder A.
Publication year - 2021
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.202004182
Subject(s) - pipeline (software) , risk analysis (engineering) , investment (military) , drug discovery , computer science , animal testing , biochemical engineering , data science , management science , business , engineering , biology , bioinformatics , political science , ecology , politics , law , programming language
In vivo models remain a principle screening tool in the drug discovery pipeline. Here, the challenges associated with the need for animal experiments, as well as their impact on research, individual/societal, and economic contexts are discussed. A number of alternatives that, with further development, optimization, and investment, may replace animal experiments are also revised.