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Stem Cell Fate: Effect of Hydroxyapatite Nanorods on the Fate of Human Adipose‐Derived Stem Cells Assessed In Situ at the Single Cell Level with a High‐Throughput, Real‐Time Microfluidic Chip (Small 51/2019)
Author(s) -
Hao Min,
He Jianlong,
Wang Chunhua,
Wang Chao,
Ma Baojin,
Zhang Shan,
Duan Jiazhi,
Liu Feng,
Zhang Yu,
Han Lin,
Liu Hong,
Sang Yuanhua
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201970279
Subject(s) - nanorod , microfluidic chip , cell , microfluidics , in situ , stem cell , cell fate determination , nanotechnology , adipose tissue , cellular differentiation , chemistry , materials science , microbiology and biotechnology , single cell analysis , biophysics , biology , biochemistry , organic chemistry , transcription factor , gene
In article number 1905001, Lin Han, Hong Liu, Yuanhua Sang, and co‐workers design a microfluidic single cell chip with a protein chip to study the effect of hydroxyapatite (HAp) on the osteogenic differentiation of human adiposederived stem cells (hADSCs) in situ at the single cell level. The detection of secretory proteins confirms that HAp nanorods enhance osteogenic differentiation at the single cell level.