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Drug Delivery: Sequentially Site‐Specific Delivery of Apoptotic Protein and Tumor‐Suppressor Gene for Combination Cancer Therapy (Small 40/2019)
Author(s) -
Chen Xiaojie,
Zhu Qiuwen,
Xu Xiao,
Shen Shiyang,
Zhang Ying,
Mo Ran
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201970218
Subject(s) - liposome , suppressor , drug delivery , gene delivery , apoptosis , cancer , cancer research , cancer therapy , gene , genetic enhancement , nanotechnology , biology , materials science , biochemistry , genetics
In article number 1902998, Ran Mo and co‐workers develop a liposome‐based assembly for site‐specific delivery of an apoptotic protein and a tumor‐suppressor gene. The liposome can deliver cargoes to their differential intracellular targets as represented by the melting snow from the mountains feeding two rivers, therefore enhancing the combined anticancer effect as represented by the rivers joining to form the waterfall with powerful potential energy.