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ECM‐Anchored Microspheres: Mesenchymal Stem Cell Capping on ECM‐Anchored Caspase Inhibitor–Loaded PLGA Microspheres for Intraperitoneal Injection in DSS‐Induced Murine Colitis (Small 23/2019)
Author(s) -
Pathak Shiva,
Regmi Shobha,
Shrestha Prakash,
Choi Inho,
Doh KyoungOh,
Jeong JeeHeon
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201970121
Subject(s) - mesenchymal stem cell , extracellular matrix , materials science , plga , microsphere , viability assay , stem cell , biomedical engineering , cell , microbiology and biotechnology , nanotechnology , chemistry , chemical engineering , medicine , biochemistry , nanoparticle , engineering , biology
In article number 1901269 , Jee‐Heon Jeong and co‐workers synthesize a dopamine‐modified stabilizer which remains interpenetrated on the surface of microspheres and acts as a glue for extracellular matrix (ECM) attachment. The cell‐friendly, ECM‐modified microspheres are loaded with IDN6556 to enhance viability of mesenchymal stem cells.