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Cells at Wrinkled Interfaces: Laser‐Assisted Strain Engineering of Thin Elastomer Films to Form Variable Wavy Substrates for Cell Culture (Small 21/2019)
Author(s) -
Tomba Caterina,
Petithory Tatiana,
Pedron Riccardo,
Airoudj Aissam,
Di Meglio Ilaria,
Roux Aurélien,
Luchnikov Valeriy
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201970113
Subject(s) - elastomer , materials science , substrate (aquarium) , laser , stiffening , composite material , strain (injury) , optics , medicine , physics , oceanography , geology
In article number 1900162 , Caterina Tomba, Valeriy Luchnikov, and co‐workers present a versatile approach to produce curved surfaces with dynamic and variable topographic parameters. Mid‐infrared laser exposure allows for surface stiffening of an elastomer that is suitable as wavy substrate to grow cells on smooth and more realistic micro‐environments. The wrinkled geometry is tuned by controlling the shape and stretching rate of the substrate and the irradiation parameters of the laser. This technique is easily accessible for further studies on cell migration and cell fate determination.