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Drug Delivery: Drug‐Controlled Release Based on Complementary Base Pairing Rules for Photodynamic–Photothermal Synergistic Tumor Treatment (Small 3/2019)
Author(s) -
Zhan Qichen,
Shi Xianqing,
Zhou Jiahong,
Zhou Lin,
Wei Shaohua
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201970019
Subject(s) - photothermal therapy , drug , drug delivery , thymine , nanoparticle , nanotechnology , photodynamic therapy , chemistry , combinatorial chemistry , materials science , dna , pharmacology , medicine , biochemistry , organic chemistry
In article number 1803926 , Lin Zhou, Shaohua Wei, and co‐workers design and prepare a controlled release drug delivery system based on the DNA complementary base paring rules in biology between adenine (A) modified polydopamine nanoparticles (A‐PDA) and thymine (T) modified zinc phthalocyanine (T‐ZnPc). T‐ZnPc is effectively released from A‐PDA by an NIR light‐triggered heating process at the tumor position to provide satisfactory tumor suppression efficacy.