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Nanoparticle‐Regulated Semiartificial Magnetotactic Bacteria with Tunable Magnetic Moment and Magnetic Sensitivity
Author(s) -
Li Qilong,
Chen Haitao,
Feng Xueyan,
Yu Chanchan,
Feng Feng,
Chai Yahong,
Lu Pan,
Song Tao,
Wang Xiuyu,
Yao Li
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201900427
Subject(s) - magnetotactic bacteria , microscale chemistry , magnetic nanoparticles , nanorobotics , nanotechnology , magnetization , materials science , nanoparticle , magnetic moment , magnetic field , physics , magnetite , condensed matter physics , mathematics education , mathematics , quantum mechanics , metallurgy
Micro‐/nanomotors are widely used in micro‐/nanoprocessing, cargo transportation, and other microscale tasks because of their ability to move independently. Many biological hybrid motors based on bacteria have been developed. Magnetotactic bacteria (MTB) have been employed as motors in biological systems because of their good biocompatibility and magnetotactic motion in magnetic fields. However, the magnetotaxis of MTB is difficult to control due to the lack of effective methods. Herein, a strategy that enables control over the motion of MTB is presented. By depositing synthetic Fe 3 O 4 magnetic nanoparticles on the surface of MTB, semiartificial magnetotactic bacteria (SAMTB) are produced. The overall magnetic properties of SAMTB, including saturation magnetization, residual magnetization, and blocking temperature, are regulated in a multivariate and multilevel fashion, thus regulating the magnetic sensitivity of SAMTB. This strategy provides a feasible method to manoeuvre MTB for applications in complex fluid environments, such as magnetic drug release systems and real‐time tracking systems. Furthermore, this concept and methodology provide a paradigm for controlling the mobility of micro‐/nanomotors based on natural small organisms.