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pH Regulated Assembly: Temporally Programmed Disassembly and Reassembly of C3Ms (Small 46/2018)
Author(s) -
Cingil Hande E.,
Meertens Nicky C. H.,
Voets Ilja K.
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870220
Subject(s) - polyfluorene , coacervate , micelle , polyelectrolyte , copolymer , dissociation (chemistry) , fluorescence , conjugated system , self assembly , nanotechnology , chemistry , materials science , polymer chemistry , combinatorial chemistry , polymer , organic chemistry , chromatography , aqueous solution , physics , quantum mechanics
In article number 1802089 , Ilja K. Voets and co‐workers report on the temporally programmed, self‐regulating formation and dissociation of complex coacervate core micelles (C3Ms) comprising a double hydrophilic block copolymer and a pH‐responsive polyfluorene‐based conjugated polyelectrolyte as building blocks and a molecular sensor (doxorubicin HCl) as cargo. The latter (macro)molecular probes report in‐situ on micellar assembly states and cargo release via their unique fluorescence response.