Insulin Delivery Platforms: Multiresponsive Supramolecular Theranostic Nanoplatform Based on Pillar[5]arene and Diphenylboronic Acid Derivatives for Integrated Glucose Sensing and Insulin Delivery (Small 38/2018) | Zendy

Zuo Minzan | Zendy; Qian Weirui | Zendy; Xu Zuqiang | Zendy; Shao Wei | Zendy; Hu XiaoYu | Zendy; Zhang Dongmei | Zendy; Jiang Juli | Zendy; Sun Xiaoqiang | Zendy; Wang Leyong | Zendy

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Insulin Delivery Platforms: Multiresponsive Supramolecular Theranostic Nanoplatform Based on Pillar[5]arene and Diphenylboronic Acid Derivatives for Integrated Glucose Sensing and Insulin Delivery (Small 38/2018)

Author(s) -

Zuo Minzan,

Qian Weirui,

Xu Zuqiang,

Shao Wei,

Hu XiaoYu,

Zhang Dongmei,

Jiang Juli,

Sun Xiaoqiang,

Wang Leyong

Publication year - 2018

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.201870176

Subject(s) - insulin delivery , insulin , supramolecular chemistry , pillar , chemistry , delivery system , nanotechnology , combinatorial chemistry , materials science , pharmacology , medicine , diabetes mellitus , endocrinology , type 1 diabetes , organic chemistry , engineering , molecule , structural engineering

In article number 1801942 , Xiao‐Yu Hu, Dongmei Zhang, Juli Jiang, Leyong Wang, and co‐workers develop a closed–loop insulin delivery platform based on a supramolecular strategy. Insulin can be transported to the blood vessel through this multiple stimuli‐responsive system. Under hyperglycemic conditions, the in situ generated H 2 O 2 and acidic microenvironment leads to the efficient release of insulin.

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