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Nanobioimaging: Intrinsically Fluorescent, Stealth Polypyrazoline Nanoparticles with Large Stokes Shift for In Vivo Imaging (Small 36/2018)
Author(s) -
Mane Shivshankar R.,
Hsiao ILun,
Takamiya Masanari,
Le Dao,
Straehle Uwe,
BarnerKowollik Christopher,
Weiss Carsten,
Delaittre Guillaume
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870162
Subject(s) - polyethylene glycol , stokes shift , fluorescence , nanoparticle , nanotechnology , zebrafish , biocompatible material , in vivo , materials science , macromolecule , biophysics , chemistry , biomedical engineering , biochemistry , physics , optics , biology , medicine , microbiology and biotechnology , gene
In article number 1801571 , Christopher Barner‐Kowollik, Carsten Weiss, Guillaume Delaittre, and co‐workers report the straightforward synthesis of biocompatible stealth fluorescent nanoparticles. A mild photopolycondensation provides a polypyrazoline macromolecular chain, exhibiting a large Stokes shift, attached to a polyethylene glycol segment. The nanoparticles made thereof circulate for extended periods of time in the blood stream of model zebrafish embryos and are therefore promising for advanced bioimaging.