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Exosome‐Based Nanomedicine: Cloaked Exosomes: Biocompatible, Durable, and Degradable Encapsulation (Small 34/2018)
Author(s) -
Kumar Sumit,
Michael Issac J.,
Park Juhee,
Granick Steve,
Cho YoonKyoung
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870154
Subject(s) - microvesicles , nanomedicine , nanotechnology , surface modification , biocompatible material , materials science , exosome , tannic acid , nanoparticle , microfluidics , encapsulation (networking) , chemistry , biomedical engineering , computer science , organic chemistry , biochemistry , medicine , computer network , microrna , gene
In article number 1802052 , Yoon‐Kyoung Cho and co‐workers report the encapsulation of exosomes with a nanofilm of supramolecular coordination complexes of ferric ion and tannic acid using a droplet‐based microfluidic platform. The “armored exosomes” are well protected against external stress, especially ultra‐violet irradiation and elevated temperature. On‐demand chemical degradation and further surface functionalization capabilities open up new applications beyond their native functions.