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Adjustable Fluidic Nanomixing: Amplification‐Free Multi‐RNA‐Type Profiling for Cancer Risk Stratification via Alternating Current Electrohydrodynamic Nanomixing (Small 17/2018)
Author(s) -
Koo Kevin M.,
Dey Shuvashis,
Trau Matt
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870075
Subject(s) - electrohydrodynamics , fluidics , rna , materials science , risk stratification , nanotechnology , biomedical engineering , medicine , biology , chemistry , electrical engineering , engineering , gene , genetics , electrode
In article number 1704025 , Matt Trau and co‐workers report the use of alternating current electrohydrodynamic (ac‐EHD) fluidic manipulation to create an adjustable nanoscaled mixing effect to optimally enhance traditionally‐slow probe‐RNA target hybridization. This is a novel approach for amplification‐free multi‐RNA type profiling, with high detection sensitivity and reliability for use in cancer liquid biopsies.

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