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Immunoassays: Dielectrophoresis‐Based Protein Enrichment for a Highly Sensitive Immunoassay Using Ag/SiO 2 Nanorod Arrays (Small 12/2018)
Author(s) -
Cao Zhen,
Zhu Yu,
Liu Yang,
Dong Shurong,
Chen Xin,
Bai Fan,
Song Shengxin,
Fu Junxue
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870050
Subject(s) - dielectrophoresis , nanorod , immunoassay , nanotechnology , materials science , nanoparticle , protein detection , chromatography , chemistry , antibody , microfluidics , biology , immunology
In article number 1703265 , Junxue Fu and co‐workers fabricate a dielectrophoresis (DEP) device integrated with versatile nanorod arrays for highly effective and rapid protein enrichment and detection. First, target antigen proteins are concentrated to an antibody binding region, then the immunoassays are performed, and consequently the detection signal is greatly enhanced while the incubation time required for signal saturation is notably reduced due to the enrichment of biomarkers.