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Neutrophil Phenotyping: A Novel Microdevice for Rapid Neutrophil Purification and Phenotyping in Type 2 Diabetes Mellitus (Small 6/2018)
Author(s) -
Tay Hui Min,
Dalan Rinkoo,
Li King Ho Holden,
Boehm Bernhard O.,
Hou Han Wei
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870025
Subject(s) - neutrophil extracellular traps , type 2 diabetes mellitus , diabetes mellitus , chemotaxis , type 1 diabetes , absolute neutrophil count , immunology , medicine , chemistry , inflammation , neutropenia , endocrinology , receptor , toxicity
Rapid neutrophil profiling using a drop of blood is imperative for point‐of‐care risk stratification and precision medicine approaches in type 2 diabetes mellitus. In article number 1702832 , Bernhard O. Boehm, Han Wei Hou, and co‐workers develop and clinically validate a novel integrated neutrophil purification and phenotyping (chemotaxis and formation of neutrophil extracellular traps (NETosis)) microfluidic device to demonstrate the prognostic potential of neutrophil biomarkers.