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Biomedicine: A 3D Real‐Scale, Biomimetic, and Biohybrid Model of the Blood‐Brain Barrier Fabricated through Two‐Photon Lithography (Small 6/2018)
Author(s) -
Marino Attilio,
Tricinci Omar,
Battaglini Matteo,
Filippeschi Carlo,
Mattoli Virgilio,
Sinibaldi Edoardo,
Ciofani Gianni
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201870024
Subject(s) - lithography , nanotechnology , microfluidics , materials science , biomedicine , soft lithography , confocal , two photon excitation microscopy , scale (ratio) , biocompatible material , biomedical engineering , optoelectronics , optics , physics , fluorescence , bioinformatics , engineering , fabrication , biology , medicine , alternative medicine , pathology , quantum mechanics
In article number 1702959 , Attilio Marino, Omar Tricinci, Edoardo Sinibaldi, Gianni Ciofani, and co‐workers fabricate a real‐scale, biohybrid and biomimetic microfluidic model of the blood‐brain barrier through two‐photon lithography and characterize it in vitro. This image represents the concept of the approach, from the design to the cell testing, with a merging of computer‐assisted drawing, scanning electron imaging, and confocal imaging of the device.