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Carbon Dots for In Vivo Bioimaging and Theranostics
Author(s) -
Du Jianjun,
Xu Ning,
Fan Jiangli,
Sun Wen,
Peng Xiaojun
Publication year - 2019
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201805087
Subject(s) - photothermal therapy , nanotechnology , nanomedicine , biocompatibility , photodynamic therapy , materials science , nanoparticle , chemistry , organic chemistry , metallurgy
Carbon dots (CDs), a kind of carbon material discovered accidentally, exhibit unexpected advantages in fluorescence imaging/sensing such as photostability, biocompatibility, and low toxicity. For emerging theranostics, an interdiscipline created by integrating therapy and diagnostics, CDs are good candidates when they are combined with targeted chemo/gene/photodynamic/photothermal therapeutic moieties. Here, the development of CDs in nanomedicine is reviewed from their use as original imaging agents and/or drug carriers to multifunctional theranostic systems. Finally, the challenges and prospects of the next‐generation of CD‐based theranostics for clinical applications are also discussed.